Comments on: Vicodin (Opiate) Tolerance Development

By: Renos

Renos — Sat, 30 Jul 2011 16:34:26 +0000

The math is correct but is not escalating. It’s curve which will reach a limit. That means that after a while the dose will rise to a certain limit but will never be more and more. I have made a calculation in Excel with an intake of Morphine over 44 hours. Every 4 hours a dose of 30 mg and the morphine has a half-life of 2 hours. At 44 hours you see a doses of 44,9927 mg. What you see is an E-curve with a limit of 45 mg concentration. So there is no escalation and this theory is not the cause of Tolerance develpoment.

By: Need some inspiration PLEASE

Need some inspiration PLEASE — Tue, 24 May 2011 02:11:57 +0000

josh;
don’t know ya “yet” but we could use some testosterone on “about page” i am on day 10 working on day 11. from 20 yellow norco 10s a day for many years.. i have an amazing job and great friends and even with all that i couldn’t have done any of it without these great friends i have made on here; total support group and can understand what we are going through. just FYI

By: Metoo

Metoo — Fri, 25 Feb 2011 14:44:42 +0000

Hey, Josh, if you wish to, you should swing over to the “about” page….lots of us hang out over there, and are committed to helping each other! Come join us if you wish!! We welcome you!!!!

By: Josh

Josh — Fri, 25 Feb 2011 02:26:53 +0000

This site is awsome and so helpful. ThankS everyone.

By: Kris

Kris — Tue, 13 Jul 2010 15:42:49 +0000

thanks for putting it into perspective with the timetable…that is and hopefully soon to be was me. ….favorite line from Mr. Brownstone. “a little wouldnt do it so the little got more and more” . this is a great site!

By: No Painkillers: Pain Management Techniques Part 1 | VicodinWithdrawal.org

No Painkillers: Pain Management Techniques Part 1 | VicodinWithdrawal.org — Thu, 11 Jun 2009 06:00:32 +0000

[...] tolerance develops, it gets harder and harder to effectively manage the sometimes excrutiating pain that accompanies a [...]