Comments on: Endorphin Deficiency Syndrome (EDS) Do You Have It?

By: Jade

Jade — Thu, 17 Jun 2010 12:08:16 +0000

Long before I ever heard of EDS I posted that I felt I was lacking in natural “feel good” chemicals. After a two year run on oxys I am on 30 mgs of methadone a day and although it kind of bothers me, I’ll probably need to be on it for life to compensate for the endorphins my body lacks in producing. Maybe one day modern medicine will figure out a way to naturally fix our broken endorphin manufacturing processes but until then this is my best bet at leading a normal life.

By: adf

adf — Wed, 12 May 2010 05:49:39 +0000

They will never look into this theory soon enough. Already, after decades of millions of failed serotonin/dopamine/norepinephrine courses, the research establishments is focusing on ‘other’ ways to boost the same biochemicals, apparently with the exception of GABA. But even GABA boosters won’t likely help those who suffer due to low endorphin levels. Sit in and wait for the next “thought to increase serotonin levels” pill or device theory. Or the next norepinephrine booster, or hear this. Amazingly, the next norepinephrine AND serotonin booster! See, if neither helped many, and the combination has shown to fail to help many, it must be. Ah, there’s where dopamine comes in, which also has shown to fail to help many too. Just wait for the next “serotonin/norepinephrine/dopamine” booster while the endorphin theory is 99% rejected, even while the same people recommend exercise which they also say boosts endorphins! But nah, it still must be “serotonin/norepinephrine/dopamine”.

By: OneDayAtaTime

OneDayAtaTime — Wed, 28 Apr 2010 13:41:14 +0000

That artical on the top IS ME!!!!! Very well put. Though I am one that cant work out to get that high. My addiction started in 2003 when I was reareanded and fractured my C-5 in my neck chugging along . in 2005 was rearended again and that was it. Stuck at home had the breaks put onto my life and needed to fill the time…… I loved how I felt on them!!!!! Have you heard of any new medications Dr.s use now. I have done Prozac, and was more blah than before I discovered Vicoden, OH BTW I am on day 3 of no Vicoden Hagen in there

By: Neonurse

Neonurse — Wed, 10 Feb 2010 20:54:25 +0000

Thanks so much for starting this website with such great information! I began using opiates approximately 4 years ago due to aggravation of an old back injury. For 10 years I had been having this pain every month for app. 2-3 days and I always just suffered through however 4 years ago it just started up and never stopped. It became a continual nightmare of low back and leg pain. I was hesitant to even take pain meds due to the bad press that they get but it stopped the pain and that was all I cared about! Now four years later it takes 3-4 times the original dose to even make a dent in the pain. I go through periods where, when I run out before my next appt., I think I’m just going to stop the madness but the pain and the depression, not to mention the fatigue, nearly paralyze me and I can’t function! When I don’t have anything to take the pain is so bad I think I might lose my mind and it’s like a vicious cycle. I want to stop but I don’t know how to stop the pain. I was so glad to read about EDS and one comment I’ve read previously really hit home with me. Someone asked if anyone had ever heard the phrase “runners high” and never understood it before, and that was something that was so true for me. I have never, ever felt anything but extreme fatigue and pain from exercising. Now I’m back in my usual position of being out of meds and wondering if my body is simply telling itself it’s in pain in order to get the opiods it wants or if I am actually having legitimate pain. It’s so damned confusing. I go through this battle month after month and I am so sick and tired of it. I am a single parent so not working is not an option and I don’t know where to go from here. Thanks so much for listening, I don’t know how much sense I’ve made here but I’m so glad I’m not the only one who is going through this. I might talk to my doc about the LDN and see what she thinks. I’m so afraid to let any of my doctors know that I’m having a problem because so many of them are not very understanding. I did try pot on several occasions and it has had little to no effect on me at all. My friend with whom I do this thinks that something is wrong with my body since I don’t get any effect from it but I keep trying to tell him that everyone’ s body reacts differently to different meds. Ever since I was younger I’ve always responded the opposite of other people to most medications and usually require more initially to get any effect. Sorry for such a long post but I’m really hurting and it made me feel a little better psychologically to get some of this off my chest. Thanks so much for this site and all your great info!

By: minderbinder

minderbinder — Thu, 28 Jan 2010 10:20:22 +0000

Hey! Just stumbled upon this site – I’ve had my last detox 15 years ago and since then i feel like …, well, “shit”. For the first few years i believed it would become better after time, but it didn’t, even with beeing prescribed more and more antidepresives and pain med’s (non-op). So thanks a lot for your site and the LDN hint!

By: Brainchemist

Brainchemist — Sun, 27 Dec 2009 19:30:45 +0000

EDS is, also because the contribution of brilliant pioneers like Rearden, getting more and more recognition over the years. LDN is for most people who suffer from it a safe cure with minimum risk and side effects. I strongly advise patients to try LDN first before obtaining endorphins from an external source like opiates, just as Reardon explains on his great site ‘Ignorance Kills’. Good luck to you all!

By: carie martinez

carie martinez — Sat, 19 Dec 2009 01:03:23 +0000

i NEVER realized all this stuff is was and is happening my mind is OUT OF WACK lately due to my detox method which is to go as low as i can and wait longer intervals befor taking another milligram i simply cannot be down and out due to the job i have and being a single parent gonna check out this naltrexone all this makes since and ive been a chocoholic last week and didnt know why now i do! but my body has been wanting more risky behaviors and excitment too! like fighting,exercising and other things

By: Rearden Metal

Rearden Metal — Mon, 19 Oct 2009 23:35:48 +0000

Hi Adam, and thanks for linking to my site! LDN definitely works (for E.D.S. depression AND opiate PAWS), without all the side effects and other assorted baggage that accompany an opiate habit.

Preparing LDN from 50mg naltrexone pills is easy enough- Just find a little glass dropper bottle, count out exactly 200 drops of distilled water, deposit the 50mg naltrexone pill, and shake (It’ll dissolve by itself after a few minutes- no need to crush or grind it). Once you have this prepared, just remember that every 4 drops of LDN solution equal 1mg naltrexone. The effective LDN dosage for most people is 2.5 to 4.5 mg before bed (which would be 10 to 18 drops of LDN solution).

BTW, in case you were wondering why it’s been over a year since I last updated ProhibitionKills.com , now that I’m on LDN and off all the opiates, I may be in better shape physically- but my creative writing skills have virtually evaporated. (Without their opiate habits, could Edgar Allen Poe, Howard Hughes & Kurt Cobain have exuded all that creative brilliance? I wonder.)

I’m just glad I’m not the only one trying to spread the word…

By: Adam

Adam — Wed, 19 Aug 2009 06:30:06 +0000

JamesK,

Thanks so much for the great advice. Can you share with us how you were able to obtain the naltrexone in a low dose form? From what I know most physicians only prescribe at the regular dose of around 50mg.

Best of luck to you, and God Bless

By: JamesK

JamesK — Fri, 07 Aug 2009 01:46:34 +0000

Hi everyone,

I too had issues with opiates. I was put on them 18 years ago for a severe broken foot and then back pain, headaches etc. I never liked opiates but when you are hurting, hey you will take what gets rid of the pain. I finally got sick of them and slowly withdrew off of them. . However, after a few months from my last dose I went into major PAWS (post acute withdrawal syndrome). The symptoms of PAWS were awful. No sleep, restlessness, over reactive emotions, discoordination, and dreaded short term memory problems. As well my blood pressure would shoot up to 150/100. Terrible. Well, I knew I had to slay this dragon. So I did. I began to exercise daily even when I did not feel like it, take amino acids, vitamins, and methionine supplements. This was all to restore my neurotransmitter balance in the brain.

What essentially happens during physical withdrawal is that your body forgets how to make its own endorphins because you have been feeding it exogenous endorphins via the medication. Then what happens is your adrenaline or sympathetic nervous system becomes unchecked, hence the restless legs, high blood pressure, pounding heart etc. Endorphins balance your adrenaline system in the brain via an area called the locus ceruleus and the limbic system.

It takes time to rebuild the balance of neurotrasmitters and receptors. So hence the use of vitamins and exercise. However, it did not take the full symptoms of PAWS totally away, so I researched some more. In comes low dose naltrexone at 3mg to 4.5 mg each night before bedtime. What a wonder drug. Non addictive, low profile of side effects at that dose and immune powering and endorphin releasing effects. I now feel fantastic. No more PAWS, it has slowly diminished. I feel normal again. Only side effect is a slight mild dizziness once in a blue moon but very mild.
It needs to be prescribed by a physician and then filled ata compounding pharmacy. Here is a website where it is used for multiple sclerosis and other automimmune diseases: http://www.lowdosenaltrexone.org

As well, I have not suffered from a cold or illness in over 8 months as low dose naltrexone boosts your immune system by rebound effect by way of an endorphin surge throughout the day. This surge however is natural and endogenous therefore non-addictive. Talk to your addiction specialists. There is alot of research out there on animals and human subjects to justify its use for addiction medicine. If you are assessed and there are no contraindications to take it then demand it. It will restore your life. Good luck everyone and God Bless,